By Patricia L. Traynor, Robert Frederick, Muffy Koch.
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Extra info for Biosafety and risk assessment in agricultural biotechnology : a workbook for technical training
Not all GMOs pose an environmental cases, conventional greenhouses can be made suit- risk; of those that may cause harmful effects, not able for GMOs by simple refurbishing and minor all pose the same level of risk. Accordingly, structural upgrades. For higher levels of contain- biosafety reviewers strive to tailor risk-manage- ment, facilities may have to meet such speciﬁ- ment procedures to the nature and magnitude of an cations as controlled and ﬁltered airﬂow, systems identiﬁed risk. Some of these strategies are dis- to control and disinfect water leaving the facility, cussed in the following sections.
However, with • May contribute knowledge and experience in the use of organisms with novel traits organization, or body the emergence of modern biotechnology, specula- • Can be used to verify assumptions made in a risk assessment tion about potential harm from GMOs introduced • Should be used to evaluate whether risk-management measures into the environment has shifted the focus of moni- used are appropriate and effective. toring to following the fate of these organisms and —United Nations Environment Programme (UNEP), 1996 the transgenes they carry and to be vigilant for unanticipated consequences.
Marker genes are included in the level. Attention generally is focused on limiting risk segment of inserted DNA in order to distinguish by proper handling and use of various preventive cells that contain the new genes from those that do measures. In fact, opportunities to manage poten- not. Some marker genes encode enzymes that lead tial or identiﬁed risks can be found throughout the to the production of a pigment or ﬂuorescent light, process of developing and testing genetically engi- allowing easy identiﬁcation of GM cells.