2011-2012 Basic and Clinical Science Course, Section 10: by George A. Cioffi MD

By George A. Cioffi MD

Subject matters on glaucoma contain the epidemiologic facets; hereditary and genetic elements; intraocular strain and aqueous humor dynamics; and medical overview, clinical administration and surgical treatment. comprises a variety of pictures illustrating affliction entities and surgical options. final significant revision 2008 2009.

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Additional resources for 2011-2012 Basic and Clinical Science Course, Section 10: Glaucoma (Basic & Clinical Science Course)

Sample text

Such hypothetical derangement could be related to abnormal vessels or to circulating vasoactive substances, for example. Current thinking regarding glaucomatous optic neuropathy recognizes that both vascular and mechanical factors probably contribute to damage. The glaucomas are likely a heterogeneous family of disorders, and the ganglion cell death seen in glaucomatous optic neuropathy may be mediated by many factors. Active investigations continue to examine the potential role in glaucomatous optic neuropathy of processes such as excitotoxicity, apoptosis, neurotrophin deprivation, ischemia, and autoimmunity.

Axenfeld-Rieger syndrome, an autoso mal dominant disorder with variable penetrance, is associated with microdontia (small, peglike incisors), hypodontia (decreased number of teeth), and anodontia (focal absence of teeth). Maxillary hypoplasia may also be present. Glaucoma occurs in 50% of cases in late childhood or adulthood. A number of entities are associated with signs of increased episcleral venous pressure. The presence of a facial cutaneous angioma (nevus flammeus, or port-wine stain) can indicate eneephalofaeial angiomatosis (Sturge- Weber syndrome).

Doherty M], Zaman ML. Human corneal thickness and its impact on intraocular press ure measures: a review and meta-analysis approach. Surv Ophthalm ol. 2000;44:367- 408 . Gordon MA, Beiser JA, Brandt JA, et al. The Ocular Hypertension Treatment Study: baseline fac tors that pred ict the onset of primary open-angle glaucoma. Arch Ophtha/mol. 2002; 120( 6);7 14- 720. Mills RP. If intraocular pressure measurement is on ly an estimate-then what? Ophthalmology. 2000;107;1807- 1808. Shah S. Accurate intraocular pressure measu rement-the myth of modern ophthalmology?

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